Neurobiological and translational fatigue research laboratory
University of Leeds, United Kingdom
OUR RESEARCH
Research has resumed!




We are currently recruiting chronic (at least 6-months post-stroke) Stroke Survivors for whom fatigue is a prominent symptom into a new study aiming to understand the physiological and cognitive mechanisms underlying fatigue.
The study includes 1-2 testing sessions at the University of Leeds and will involve you taking part in some screening tasks and questionnaires, and then taking part in some behavioural tasks. There will also be a session using TMS (transcranial magnetic stimulation). Some participants may also be asked to take part in an MRI session where MRI imaging of your brain will be collected whilst you do a grip force task.
You will be able to see an information sheet of the study after pressing the link below and will be asked to complete an anonymous online screening form. Please read through all the instructions carefully and contact a member of the research team at research.effortlab@leeds.ac.uk for more information.
Techniques
Brain Imaging


Non-invasive Brain Stimulation
Behaviour
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Public Engagement
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Brain Imaging
Non-invasive Brain Stimulation
Behaviour
Public Engagement
Our lab uses EEG (electroencephalography) and fMRI (functional Magnetic Resonance Imaging) to study how movement related sensory information is processed in patients with chronic pathological fatigue. We study sensory perception across different sensory modalities, from vision, hearing to proprioception.
Our lab uses various non-invasive brain stimulation techniques including Transcranial Magnetic Stimulation (TMS) and transcranial Electrical Stimulation (tES) to examine the connections between different brain regions and develop brain-based therapeutic interventions in those with chronic pathological fatigue.
Our lab uses a range of paradigms to study behaviour and decision making in patients with chronic pathological fatigue. Specifically, we are interested in how the perception of effort is associated with the severity of fatigue
'Experiencing Fatigue' is a collaborative arts and research project involving stroke survivors, neuroscientists and artist Sofie Layton. The project explores stroke survivors' experiences of post-stroke fatigue through artistic media.
These have informed a physical installation and online showcase entitled,
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'Ensnared: The Inescapable Reality of Fatigue'.
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Our overarching aim is to make visible this invisible condition and deepen everyone's understanding of the physical and emotional challenges involved in tackling post-stroke fatigue in one's everyday life. As well as this Dr Kuppuswamy hopes that the artistic expressions will help inform her scientific work.